Is Comorbid Borderline Personality Disorder in Patients With Major Depressive Episode and Bipolarity a Developmental Subtype? Findings From the International BRIDGE Study.
Is comorbid borderline personality disorder in patients with major depressive episode and bipolarity a developmental subtype? Findings from the international BRIDGE study.
Filed under: Eating Disorders
J Affect Disord. 2012 Aug 1;
Perugi G, Angst J, Azorin JM, Bowden C, Vieta E, Young AH,
BACKGROUND: The nature of the relationship between bipolar disorder (BD) and borderline personality disorder (BPD) is controversial. The aim of this study was to characterize the clinical profile of patients with BD and comorbid BPD in a world-wide sample selected during a major depressive episode (MDE). METHODS: From a general sample of 5635 in and out-patients with an MDE, who were enrolled in the multicenter, multinational, transcultural BRIDGE study, we identified 2658 subjects who met bipolarity specifier criteria. Bipolar specifier patients with (BPD+) and without (BPD-) comorbid BPD were compared on diagnostic, socio-demographic, familial and clinical characteristics. RESULTS: 386 patients (14.5%) met criteria for BPD. A diagnosis of BD according to DSM-IV criteria was significantly more frequent in the BPD- than in BPD+, while similar rates in the two groups occurred using DSM-IV-Modified criteria. A subset of the BD criteria with an atypical connotation, such as irritability, mood instability and reactivity to drugs were significantly associated withthe presence of BPD. BPD+ patients were significantly younger than BPD- bipolar patients for age, age at onset of first psychiatric symptoms and age at first diagnosis of depression. They also reported significantly more comorbid Alcohol and Substance abuse, Anxiety disorders, Eating Disorder and Attention Deficit Hyperactivity Disorder. In comparison with BPD-, BPD+ patients showed significantly more psychotic symptoms, history of suicide attempts, mixed states, mood reactivity, atypical features, seasonality of mood episodes, antidepressants induced mood lability and irritability, and resistance to antidepressant treatments. LIMITATIONS: Centers were selected for their strong mood disorder clinical programs, recall bias is possible with a cross-sectional design, and participating psychiatrists received limited training. CONCLUSIONS: We confirm in a large sample of BD patients with MDE the high prevalence of patients who meet DSM-IV criteria for BPD. Further prospective researches should clarify whether the mood reactivity and instability captured by BPD DSM-IV criteria are distinguishable from the subjective mood of an instable, dysphoric, irritable manic/hypomanic/mixed state or simply represent a phenotypic variant of BD, related to developmental factors.
HubMed – eating
Social phobia in obsessive-compulsive disorder: Prevalence and correlates.
Filed under: Eating Disorders
J Affect Disord. 2012 Aug 1;
Assunção MC, Lucas da Conceição Costa D, Mathis MA, Gedanke Shavitt R, Arzeno Ferrão Y, Rosário MC, Constantino Miguel E, Rodrigues Torres A
BACKGROUND: Social Phobia (SP) is an anxiety disorder that frequently co-occurs with obsessive-compulsive disorder (OCD); however, studies that evaluate clinical factors associated with this specific comorbidity are rare. The aim was to estimate the prevalence of SP in a large multicenter sample of OCD patients and compare the characteristics of individuals with and without SP. METHOD: A cross-sectional study with 1001 patients of the Brazilian Research Consortium on Obsessive-Compulsive Spectrum Disorders using several assessment instruments, including the Dimensional Yale-Brown Obsessive-Compulsive Scale and the Structured Clinical Interview for DSM-IV Axis I Disorders. Univariate analyses were followed by logistic regression. Results: Lifetime prevalence of SP was 34.6% (N=346). The following variables remained associated with SP comorbidity after logistic regression: male sex, lower socioeconomic status, body dysmorphic disorder, specific phobia, dysthymia, generalized anxiety disorder, agoraphobia, Tourette syndrome and binge eating disorder. LIMITATIONS: The cross-sectional design does not permit the inference of causal relationships; some retrospective information may have been subject to recall bias; all patients were being treated in tertiary services, therefore generalization of the results to other samples of OCD sufferers should be cautious. Despite the large sample size, some hypotheses may not have been confirmed due to the small number of cases with these characteristics (type 2 error). Conclusion: SP is frequent among OCD patients and co-occurs with other disorders that have common phenomenological features. These findings have important implications for clinical practice, indicating the need for broader treatment approaches for individuals with this profile.
HubMed – eating
Changes in eating behaviors and body weight in Koreans: The Healthy Twin Study.
Filed under: Eating Disorders
Nutrition. 2012 Aug 1;
Song YM, Lee K, Sung J, Yang YJ
OBJECTIVE: We examined the associations between eating behavior at baseline and changes in eating behaviors with weight change, and quantified the contribution of eating behavior and genetic effects on weight change. METHODS: A prospective study of male (n = 482) and female (n = 879) Korean twins and family members who were weighed and assessed twice (baseline visit from December 2005 to December 2008, follow-up visit 2.7 ± 0.9 y later) using eating behavior subscales (external, emotional, and restrained eating) as measured by the Dutch Eating Behavior Questionnaire. RESULTS: After adjusting for family variables, eating behavior subscales at baseline, changes in emotional and restrained eating, age, education, weight, and lifestyle at baseline, and menopausal status at baseline (for women), an increase in external eating was significantly associated with weight gain in men (1.08, 95% confidence interval 0.41-1.74) and in women (0.63, 95% confidence interval 0.13-1.12). None of the three eating behavior subscales at baseline or changes in emotional and restrained eating were associated with weight change. Eating behavior at baseline and changes in those eating behaviors accounted for 4% and 1% of the changes in weight in men and women, respectively. Additive genetic effects in women contributed to 18% of weight change, whereas in men there was no genetic contribution. CONCLUSIONS: These results suggest that an increase in external eating may predict adult weight gain in men and women. However, the relative contribution of eating behavior to weight change was very small, whereas the contribution of genetic effects on weight change was significant in women.
HubMed – eating
The importance of full-time work for urban adults’ mental and physical health.
Filed under: Eating Disorders
Soc Sci Med. 2012 Jul 27;
Rosenthal L, Carroll-Scott A, Earnshaw VA, Santilli A, Ickovics JR
Unemployment and underemployment have adverse mental and physical health consequences, such as increased stress and depression. Health damaging behaviors like unhealthy eating, smoking, and alcohol use may be used to cope, contributing to chronic disease risk. In this adverse economic climate, it is vital to understand the health implications of unemployment and underemployment as well as underlying mechanisms. A randomized household survey of adults in six low resource communities was conducted in New Haven, Connecticut in 2009, yielding a sample of 1205 (73% participation) racially diverse adults (61% Black, 20% Latino, 12% White) ages 18-65 (61% women). We used ANOVA to test group differences and structural equation modeling to test mediation. 14.5% were unemployed and looking for work, 18.4% worked part-time, 38.2% worked full-time. Those employed full-time reported the least damaging psychological factors and health behaviors: lowest levels of stress and depression, most healthy and least unhealthy eating, most physical activity, and lowest levels of smoking and drinking. Those employed part-time fell in the middle, and those unemployed fell on the unhealthy end of all psychological and behavioral factors. Stress significantly mediated the associations of full-time employment with frequency of unhealthy eating and physical activity, and amount of cigarette smoking and alcohol consumption. Depression significantly mediated the association of full-time employment with frequency of healthy eating. Compared to <10% nationwide, rates of unemployment in this sample were high. Both those unemployed and employed part-time reported adverse health behaviors as compared to those employed full-time, partially mediated by heightened stress and depression. It is vital for the health and well-being of the nation to increase not simply employment, but specifically full-time employment. Provision of mental health services to those unemployed and underemployed should be a priority to promote healthier lifestyles and prevent costly future chronic disease. HubMed – eating
Metals concentrations in Nile tilapia Oreochromis niloticus () from illegal fish farm in Al-Minufiya Province, Egypt, and their effects on some tissues structures.
Filed under: Eating Disorders
Ecotoxicol Environ Saf. 2012 Jul 31;
Authman MM, Abbas WT, Gaafar AY
This study clarified the suitability of fishes caught from illegal fish farms to human consumption and their hazards to public health. For this purpose, the concentrations of some metals (Al, Cd, Pb, Hg and Ni) in water and Nile tilapia (Oreochromis niloticus) fish samples collected from an illegal fish farm, in addition to pathological conditions of the fish tissues, were examined. The illegal farm water was found to be heavily polluted with metals which far exceeded the permissible limits. It was found that metals accumulated in tissues of O. niloticus in concentrations higher than those of farm water. Kidney of O. niloticus contained the highest concentrations of the detected metals, while muscle and skin contained the lowest concentrations. The examination of fish tissues revealed various histopathological lesions which related directly to the pollution of the illegal farm water. Moreover, metals levels in O. niloticus muscle were higher than the maximum permissible levels for human consumption. Consequently, the flesh of fishes from the illegal farms could be considered hazardous to human health. Therefore, warning against eating fish caught from the illegal fish farms should be announced. Moreover, removal of such illegal fish farms is necessary for the public health protection.
HubMed – eating
MGH's Dr. David Herzog has brought eating disorders out in the open
Filed under: Eating Disorders
IN MAY, editors of all 19 international editions of Vogue pledged to ban models who they believe suffer from eating disorders or are younger than 16. While the move won't radically alter the glossies or end women's struggle with their body images, it's …
Read more on Boston Globe
Sleep Eating Disorder
Filed under: Eating Disorders
We have heard of eating disorders and sleep disorders but Sleep Eating Disorders – what is that? Often referred to as SED, this ailment is more of a sleep disorder rather than an eating disorder. This condition causes people involuntarily and …
Read more on Khaleej Times
Other Types of 'Disordered Eating'
Filed under: Eating Disorders
When most people hear the term 'eating disorders' they think of anorexia or bulimia. They might even think of binge eating disorder as it has begun to get more coverage in the media lately. But few people consider the other types of disordered eating …
Read more on About – News & Issues
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