Addiction Rehab: Coinciding Revolutions: How Discovery of Non-Coding DNA and RNA Can Change Our Understanding of Addiction.
Coinciding revolutions: how discovery of non-coding DNA and RNA can change our understanding of addiction.
Filed under: Addiction Rehab
Front Genet. 2012; 3: 271
Pietrzykowski AZ
The role of orexins/hypocretins in alcohol use and abuse: an appetitive-reward relationship.
Filed under: Addiction Rehab
Front Behav Neurosci. 2012; 6: 78
Kim AK, Brown RM, Lawrence AJ
Orexins (hypocretins) are neuropeptides synthesized in neurons located in the lateral (LH), perifornical, and dorsomedial (DMH) hypothalamus. These neurons innervate many regions in the brain and modulate multiple other neurotransmitter systems. As a result of these extensive projections and interactions orexins are involved in numerous functions, such as feeding behavior, neuroendocrine regulation, the sleep-wake cycle, and reward-seeking. This review will summarize the literature to date which has evaluated a role of orexins in the behavioral effects of alcohol, with a focus on understanding the importance of this peptide and its potential as a clinical therapeutic target for alcohol use disorders.
HubMed – addiction
Videos to influence: a systematic review of effectiveness of video-based education in modifying health behaviors.
Filed under: Addiction Rehab
J Behav Med. 2012 Nov 28;
Tuong W, Larsen ER, Armstrong AW
This systematic review examines the effectiveness of videos in modifying health behaviors. We searched PubMed (1975-2012), PsycINFO (1975-2012), EMBASE (1975-2012), and CINAHL (1983-2012) for controlled clinical trials that examined the effectiveness of video interventions in changing health behaviors. Twenty-eight studies comprised of 12,703 subjects were included in the systematic review. Video interventions were variably effective for modifying health behaviors depending on the target behaviors to be influenced. Video interventions appear to be effective in breast self-examination, prostate cancer screening, sunscreen adherence, self-care in patients with heart failure, HIV testing, treatment adherence, and female condom use. However, videos have not shown to be effective in influencing addiction behaviors when they are not tailored. Compared to loss-framing, gain-framed messages may be more effective in promoting certain types of health behavior change. Also, video modeling may facilitate learning of new behaviors and can be an important consideration in future video interventions.
HubMed – addiction
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