Drug and Alcohol Rehabilitation: Physical Scientists Take on Cancer.
Physical scientists take on cancer.
Filed under: Drug and Alcohol Rehabilitation
Nature. 2012 Nov 22; 491(7425): S49
Gravitz L
High-risk drug practices tighten grip on London gay scene.
Filed under: Drug and Alcohol Rehabilitation
Lancet. 2013 Jan 12; 381(9861): 101-2
Kirby T, Thornber-Dunwell M
Acid-degradable polymers for drug delivery: a decade of innovation.
Filed under: Drug and Alcohol Rehabilitation
Chem Commun (Camb). 2013 Jan 15;
Binauld S, Stenzel MH
Polymers that start degrading under acidic conditions are increasingly investigated as a pathway to trigger the release of drugs once the drug carrier reached the slightly acidic tumour environment or after the drug carrier has been taken up by cells, resulting in the localization of the polymer in the acidic endosomes and lysosomes. The advances in the design of acid-degradable polymers and drug delivery systems have been summarized and discussed in this review article. Various acid-labile groups such as acetals, orthoester, hydrazones, imines and cis-aconityl, that can undergo cleavage in slightly acidic conditions, have been employed to create polymer architectures or polymer-drug conjugates that can degrade under lysosomal and endosomal conditions, triggering the fast release of drugs or DNA.
HubMed – drug
New molecular targeted therapy and redifferentiation therapy for radioiodine-refractory advanced papillary thyroid carcinoma: literature review.
Filed under: Drug and Alcohol Rehabilitation
J Thyroid Res. 2012; 2012: 818204
Wong KP, Lang BH
Although the majority of papillary thyroid carcinoma could be successfully managed by complete surgical resection alone or resection followed by radioiodine ablation, a small proportion of patients may develop radioiodine-refractory progressive disease which is not amenable to surgery, local ablative treatment or other treatment modalities. The use of FDG-PET/CT scan for persistent/recurrent disease has improved the accuracy of restaging as well as cancer prognostication. Given that patients with RAI-refractory disease tend to do significantly worse than those with radioiodine-avid or non-progressive disease, an increasing number of phase I and II studies have been conducted to evaluate the efficacy of new molecular targeted drugs such as the tyrosine kinase inhibitors and redifferentiation drugs. The overall response rate of these drugs ranged between 0-53%, depending on whether the patients had been previously treated with these drugs, performance status and extent of disease. However, drug toxicity remains a major concern in administration of target therapies. Nevertheless, there are also ongoing phase III studies evaluating the efficacy of these new drugs. The aim of the review was to summarize and discuss the results of these targeted drugs and redifferentiation agents for patients with progressive, radioiodine-refractory papillary thyroid carcinoma.
HubMed – drug
Art Therapy Session: Using Art to Overcome Addiction – When seeking to overcome a drug or alcohol addiction, art therapy can be an incredibly powerful tool. Regardless of what artistic skill level you may have, the process of creating art can have a number of benefits for someone struggling with addiction. Not only does the process of creating art provide healing, but examining and understanding the final created product can also provide deep insight. At Clarity Way, our art therapy sessions are facilitated in a way that encourages participants to explore their personal issues. Through art therapy, our clients can better understand and evaluate personal stressors and emotions that have played a role in their addiction experience. Our experienced staff can also help clients to understand the significance of their finished work in relation to personal struggles and addiction. If you’d like to learn more about how we use art therapy as part of our holistic healing process, visit us online at www.ClarityWay.com. We invite you to read about our many types of effective drug and alcohol rehabilitation therapies. Our 24 hour help line is also available to assist you with any questions you might have about the drug and alcohol rehabilitation process 1-877-548-4794.
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