Drug and Alcohol Rehabilitation: Third-Party Drug-Test Providers Continue to Grow Nationwide.

Third-party drug-test providers continue to grow nationwide.

Filed under: Drug and Alcohol Rehabilitation

Behav Healthc. 2012 Sep-Oct; 32(5): 38, 40
Grantham D

HubMed – drug

 

Pediatric critical care, glycemic control, and hypoglycemia: what is the real target?

Filed under: Drug and Alcohol Rehabilitation

JAMA. 2012 Oct 24; 308(16): 1687-8
Tasker RC

HubMed – drug

 

Neurocognitive development of children 4 years after critical illness and treatment with tight glucose control: a randomized controlled trial.

Filed under: Drug and Alcohol Rehabilitation

JAMA. 2012 Oct 24; 308(16): 1641-50
Mesotten D, Gielen M, Sterken C, Claessens K, Hermans G, Vlasselaers D, Lemiere J, Lagae L, Gewillig M, Eyskens B, Vanhorebeek I, Wouters PJ, Van den Berghe G

A large randomized controlled trial revealed that tight glucose control (TGC) to age-adjusted normoglycemia (50-80 mg/dL at age <1 year and 70-100 mg/dL at age 1-16 years) reduced intensive care morbidity and mortality compared with usual care (UC), but increased hypoglycemia (?40 mg/dL) (25% vs 1%).As both hyperglycemia and hypoglycemia may adversely affect the developing brain, long-term follow-up was required to exclude harm and validate short-term benefits of TGC.A prospective, randomized controlled trial of 700 patients aged 16 years or younger who were admitted to the pediatric intensive care unit (ICU) of the University Hospitals in Leuven, Belgium, between October 2004 and December 2007. Follow-up was scheduled after 3 years with infants assessed at 4 years old between August 2008 and January 2012. Assessment was performed blinded for treatment allocation, in-hospital (83%) or at home/school (17%). For comparison, 216 healthy siblings and unrelated children were tested.Intelligence (full-scale intelligence quotient [IQ]), as assessed with age-adjusted tests (Wechsler IQ scales). Further neurodevelopmental testing encompassed tests for visual-motor integration (Beery-Buktenica Developmental Test of Visual-Motor Integration); attention, motor coordination, and executive functions (Amsterdam Neuropsychological Tasks); memory (Children's Memory Scale); and behavior (Child Behavior Checklist).Sixteen percent of patients declined participation or could not be reached (n = 113), resulting in 569 patients being alive and testable at follow-up. At a median (interquartile range [IQR]) of 3.9 (3.8-4.1) years after randomization, TGC in the ICU did not affect full-scale IQ score (median [IQR], 88.0 [74.0-100.0] vs 88.5 [74.3-99.0] for UC; P = .73) and had not increased incidence of poor outcomes (death or severe disability precluding neurocognitive testing: 19% [68/349] vs 18% [63/351] with UC; risk-adjusted odds ratio, 0.93; 95% CI, 0.60-1.46; P = .72). Other scores for intelligence, visual-motor integration, and memory also did not differ between groups. Tight glucose control improved motor coordination (9% [95% CI, 0%-18%] to 20% [95% CI, 5%-35%] better, all P ? .03) and cognitive flexibility (19% [95% CI, 5%-33%] better, P = .02). Brief hypoglycemia evoked by TGC was not associated with worse neurocognitive outcome.At follow-up, children who had been treated with TGC during an ICU admission did not have a worse measure of intelligence than those who had received UC.clinicaltrials.gov Identifier NCT00214916. HubMed – drug

 

The national status of tuberculosis using nationwide medical records survey of patients with tuberculosis in Korea.

Filed under: Drug and Alcohol Rehabilitation

Tuberc Respir Dis (Seoul). 2012 Jul; 73(1): 48-55
Park YS, Hong SJ, Boo YK, Hwang ES, Kim HJ, Cho SH, Na KI, Cho EH, Shin SS

The epidemiology of tuberculosis (TB) has been assessed based on the data of the analysis of TB patients notified to the surveillance system in Korea. However, the national status of TB is not validated through this surveillance system. The objective is to determine the epidemiology of TB and to understand the accurate status of TB patients treated in private institutions.Medical records of 53,579 patients who had been diagnosed with TB in 2008 were analyzed.Among 53,579 patients, the number of sputum smear positive cases was 15,639(29.2%) and the number of new cases was 39,191 (73.1%). The drug resistance rate of new cases was 5.3%, while the rate stood at 13.3% for TB patients with treatment history. The number of multi-drug resistant TB (MDR-TB) patients was 2,472 (4.6%), which consists of 2.9% of new cases and 9.3% of TB patients with prior treatment history. The number of extensively drug-resistant TB patients was 749 (1.4%), consisting of 1.1% of new cases and 2.2% of TB patients with prior treatment history. In terms of treatment outcomes, 66.4% of all TB patients, 70.5% of new cases, 64.4% of relapse cases, and 46.8% of MDR-TB cases were cured or completed. It was inferred that in 2008, the total number of TB patients reached 70,767, 145.6 per 100,000 people (95% confidence interval, 145.5~145.7).We conclude that the medical records review of the Health Insurance Review and Assessment Service (HIRA) data can be very effective in promoting the understanding of the current status of TB in private institutions.
HubMed – drug

 


 

Dwight Muhammad Qawi vs. Matthew Saad Muhammad – 1 – Background Qawi, then known as Dwight Braxton, was born in Baltimore, Maryland, but grew up in Camden, New Jersey, where he got involved with crime at a young age. He was eventually convicted of armed robbery and spent around five years in prison.[2] It was at Rahway that Braxton found his place in life. The prison had an extensive boxing program and one of its inmates, James Scott, was a light heavyweight title contender who fought several times inside the prison itself. Braxton took up the sport, and when he was released from prison in 1978, immediately became a professional boxer. Qawi’s style was most often likened to Joe Frazier and with good reason as he had trained in Fraziers Philadelphia gym as a professional. [edit] Professional career He went 1-1-1 in his first three pro fights, but then reeled off 14 straight victories to move into the world rankings at light heavyweight. The last of those wins came on September 5, 1981, when Braxton returned to Rahway to fight Scott, with the winner promised a shot at Matthew Saad Muhammad’s WBC world championship belt. Braxton won a unanimous 10-round decision. On December 19 of the same year, Braxton faced Saad Muhammad in Atlantic City. The ex-convict was the underdog against Saad, one of the most popular fighters of his generation and a fellow Hall of Famer, but Braxton defeated him on a 10th-round technical knockout and became a world champion for the first time.[3] It was shortly after this that he announced his

 

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