Eating Disorders: Should the Amounts of Fat and Protein Be Taken Into Consideration to Calculate the Lunch Prandial Insulin Bolus? Results From a Randomized Crossover Trial.
Should the Amounts of Fat and Protein Be Taken into Consideration to Calculate the Lunch Prandial Insulin Bolus? Results from a Randomized Crossover Trial.
Filed under: Eating Disorders
Diabetes Technol Ther. 2012 Dec 21;
García-López JM, González-Rodriguez M, Pazos-Couselo M, Gude F, Prieto-Tenreiro A, Casanueva F
Abstract Background: Concerning continuous subcutaneous insulin infusion (CSII), there are controversial results related to changes in glycemic response according to the meal composition and bolus design. Our aim is to determine whether the presence of protein and fat in a meal could involve a different postprandial glycemic response than that obtained with only carbohydrates (CHs). Subjects and Methods: This was a crossover, randomized clinical trial. Seventeen type 1 diabetes (T1D) patients on CSII wore a blinded continuous glucose monitoring system sensor for 3 days. They ingested two meals (meal 1 vs. meal 2) with the same CH content (50?g) but different fat (8.9?g vs. 37.4?g) and protein (3.3?g vs. 28.9?g) contents. A single-wave insulin bolus was used, and the interstitial glucose values were measured every 30?min for 3?h. We evaluated the different postprandial glycemic response between meal 1 and meal 2 by using mixed-effects models. Results: The postmeal glucose increase was 22?mg/dL for meal 1 and 31?mg/dL for meal 2. In univariate analysis, at different times not statistically significant differences in glucose levels between meals occurred. In mixed-model analysis, a time×meal interaction was found, indicating a different response between treatments along the time. However, most of the patients remained in the normoglycemic range (70-180?mg/dL) during the 3-h postmeal period (84.4% for meal 1 and 93.1% for meal 2). Conclusions: The presence of balanced amounts of protein and fat determined a different glycemic response from that obtained with only CH up to 3?h after eating. The clinical relevance of this finding remains to be elucidated.
HubMed – eating
Getting patients to target- implementing the guidelines.
Filed under: Eating Disorders
Curr Vasc Pharmacol. 2012 Nov 1; 10(6): 715-7
Giannuzzi P
All coronary patients should be advised and have the opportunity to access a comprehensive cardiovascular prevention and rehabilitation programme, addressing all aspects of lifestyle – smoking cessation, healthy eating and being physically active – together with more effective management of blood pressure, lipids and glucose. To achieve the clinical benefits of a multidisciplinary and multifactorial prevention programme we need to integrate professional lifestyle interventions with effective risk factor management, and evidence based drug therapies, appropriately adapted to the medical, cultural, and economic setting of a country. The challenge is to engage and motivate cardiologists, physicians and health professionals to routinely practice high quality preventive cardiology in hospital and community, and a health care system which invests in prevention.
HubMed – eating
What’s eating you? Bedbugs revisited (Cimex lectularius).
Filed under: Eating Disorders
Cutis. 2012 Oct; 90(4): 173-5
Patel D, Elston DM
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