Intranasal Insulin Increases Regional Cerebral Blood Flow in the Insular Cortex in Men Independently of Cortisol Manipulation.
Intranasal insulin increases regional cerebral blood flow in the insular cortex in men independently of cortisol manipulation.
Hum Brain Mapp. 2013 Aug 1;
Schilling TM, Ferreira de Sá DS, Westerhausen R, Strelzyk F, Larra MF, Hallschmid M, Savaskan E, Oitzl MS, Busch HP, Naumann E, Schächinger H
Insulin and cortisol play a key role in the regulation of energy homeostasis, appetite, and satiety. Little is known about the action and interaction of both hormones in brain structures controlling food intake and the processing of neurovisceral signals from the gastrointestinal tract. In this study, we assessed the impact of single and combined application of insulin and cortisol on resting regional cerebral blood flow (rCBF) in the insular cortex. After standardized periods of food restriction, 48 male volunteers were randomly assigned to receive either 40 IU intranasal insulin, 30 mg oral cortisol, both, or neither (placebo). Continuous arterial spin labeling (CASL) sequences were acquired before and after pharmacological treatment. We observed a bilateral, locally distinct rCBF increase after insulin administration in the insular cortex and the putamen. Insulin effects on rCBF were present regardless of whether participants had received cortisol or not. Our results indicate that insulin, but not cortisol, affects blood flow in human brain structures involved in the regulation of eating behavior. Hum Brain Mapp, 2013. © 2013 Wiley Periodicals, Inc. HubMed – eating
Effects of replacing pork backfat with emulsified vegetable oil on fatty acid composition and quality of UK-style sausages.
Meat Sci. 2013 Jul 4; 96(1): 187-194
Asuming-Bediako N, Jaspal MH, Hallett K, Bayntun J, Baker A, Sheard PR
Rapeseed and sunflower oil were used to replace pork backfat in UK-style sausages by incorporating the oils as pre-formed emulsions. Replacing the pork backfat emulsion with rapeseed emulsion at total fat content of about 12%, reduced total saturated fatty acid (SFA) composition from 38% to 14% (4.5 to 1.8g/100g), increased monounsaturated fatty acid (MUFA) composition from 45% to 59% and increased polyunsaturated fatty acid (PUFA) composition from 15% to 25%. Partial replacement of pork backfat with rapeseed at a fat content of about 20% reduced SFA from 38% to 24% (7.2 to 4.8g/100g). There were no significant differences in eating quality and overall liking other than slight differences in the attributes ‘firmness’ and ‘particle size’. Improvement in the fatty acid composition was achieved without adversely affecting colour shelf life or lipid oxidation. The study suggests that a substantial reduction in SFA can be achieved by incorporating ‘healthy’ oils in UK-style sausages without adversely affecting eating quality or shelf life. HubMed – eating
Assessment of psychometric properties of Persian version of Perceived Socio-cultural Pressure Scale (PSPS).
J Pak Med Assoc. 2013 Apr; 63(4): 468-71
Garrusi B, Garrusi S, Baneshi MR
To generate the Persian version of the Perceived Socio-cultural Pressure Scale.The study, done in Kerman, Iran, from November 2010 to February 2011, comprised 1200 volunteers. After translation and back-translation, the questionnaire’s internal consistency, criterion and construct validity were evaluated, individual and global scores of the Perceived Socio-cultural Pressure Scale were assessed between people with and without eating disorders.The mean scores for comparison were 14.7 +/- 6.64 and 21.84 +/- 10.65, giving a p-value of 0.0001. Internal and inter-item consistency were acceptable. Item-total correlation ranged from 54% to 80%. Construct and criterion validity of the scale were also acceptable.The Persian version of the Perceived Socio-cultural Pressure Scale is a competent tool for use in the general population and in individuals with eating disorders. HubMed – eating
Out of Sight – A documentary about invisible eating disorders
Http://www.proud2Bme.nl A documentary about invisible eating disorders like bulimia and EDNOS. The amount of people suffering from an invisible eating disord…