Maternal Early-Pregnancy Vitamin D Status Is Associated With Maternal Depressive Symptoms in the Amsterdam Born Children and Their Development Cohort.
Maternal Early-Pregnancy Vitamin D Status Is Associated With Maternal Depressive Symptoms in the Amsterdam Born Children and Their Development Cohort.
Filed under: Depression Treatment
Psychosom Med. 2012 Aug 9;
Brandenbarg J, Vrijkotte TG, Goedhart G, van Eijsden M
ObjectiveTo examine low maternal vitamin D status as a potential risk factor for high levels of depressive symptoms in a pregnant population.MethodsIn the Amsterdam Born Children and Their Development cohort, maternal serum vitamin D (n = 4236) was measured during early pregnancy (median, 13 weeks) and labeled “deficient” (?29.9 nM), “insufficient” (30-49.9 nM), “sufficient” (50-79.9 nM), and “normal” (?80 nM). Maternal depressive symptoms were measured by the Center for Epidemiological Studies Depression Scale at 16-week gestation. The association of vitamin D status with high levels of depressive symptoms (Center for Epidemiological Studies Depression score ?16) was assessed by multivariate logistic regression (final sample, 4101).ResultsOverall, 23% of women had vitamin D deficiency, and 21% of women had vitamin D insufficiency. Women with high levels of depressive symptoms (28%) had lower vitamin D concentrations than women with low levels of depressive symptoms (p < .001). After adjustment for constitutional factors, life-style and psychosocial covariates, and sociodemographic factors, vitamin D deficiency (odds ratio [OR], 1.48; 95% confidence interval [CI], 1.13-1.95) and insufficiency (OR, 1.44; 95% CI, 1.12-1.85) were significantly associated with high levels of depressive symptoms. Additional analyses revealed a linear trend, with an OR of 1.05 (95% CI, 1.02-1.08) for each 10-nM decrease in vitamin D status.ConclusionsIn this study, low early-pregnancy vitamin D status was associated with elevated depressive symptoms in pregnancy. Further research, using a randomized controlled design, would be required to confirm the causality of this association and the potential benefits of higher vitamin D intake for psychosocial health. HubMed – depression
The Bidirectional Association Between Depression and Insomnia: The HUNT Study.
Filed under: Depression Treatment
Psychosom Med. 2012 Aug 9;
Sivertsen B, Salo P, Mykletun A, Hysing M, Pallesen S, Krokstad S, Nordhus IH, Overland S
ObjectiveDepression and insomnia are closely linked, yet our understanding of their prospective relationships remains limited. The aim of the current study was to investigate the directionality of association between depression and insomnia.MethodsData were collected from a prospective population-based study comprising the most recent waves of the Nord-Trøndelag Health Study (HUNT) (the HUNT2 in 1995-1997 and the HUNT3 in 2006-2008). A total of 24,715 persons provided valid responses on the relevant questionnaires from both surveys. Study outcomes were onset of depression or insomnia at HUNT3 in persons not reporting the other disorder in HUNT2.ResultsBoth insomnia and depression significantly predicted the onset of the other disorder. Participants who did not have depression in HUNT2 but who had insomnia in both HUNT2 and HUNT3 had an odds ratio (OR) of 6.2 of developing depression at HUNT3. Participants who did not have insomnia in HUNT2 but who had depression in both HUNT2 and HUNT3 had an OR of 6.7 of developing insomnia at HUNT3. ORs were only slightly attenuated when adjusting for potential confounding factors.ConclusionsThe results support a bidirectional relationship between insomnia and depression. This finding stands in contrast to the previous studies, which have mainly focused on insomnia as a risk factor for the onset of depression.
HubMed – depression
Comparison of the SF-36 Five-item Mental Health Inventory and Beck Depression Inventory for the screening of depressive symptoms in chronic dialysis patients.
Filed under: Depression Treatment
Nephrol Dial Transplant. 2012 Aug 9;
van den Beukel TO, Siegert CE, van Dijk S, Ter Wee PM, Dekker FW, Honig A
BackgroundThe Beck Depression Inventory (BDI) is a standard and validated questionnaire to screen for depressive symptoms in chronic dialysis patients, but is relatively extensive to use repeatedly in clinical practice. We investigated whether the five-item Mental Health Inventory (MHI-5) of the 36-item Short-Form Health Survey Questionnaire (SF-36) could be applied to screen for depressive symptoms in dialysis patients. Moreover, we determined the optimal MHI-5 cut-off score to assess depressive symptoms.MethodsChronic dialysis patients from three centres filled out the SF-36 and the BDI. A receiver operating characteristic (ROC) curve was constructed for the MHI-5 score with BDI ?16 as reference standard to (i) calculate the area under the curve to determine whether the MHI-5 could be considered as a useful screening instrument for depressive symptoms and (ii) proxy the optimal cut-off score of the MHI-5 to assess depressive symptoms. The optimal cut-off score was determined by the value for which the sum of sensitivity and specificity had an optimum.ResultsOf 133 included patients, 23% had depressive symptoms as determined with BDI ?16. The correlation of the BDI with MHI-5 was -0.64. The area under the ROC curve was 0.82 (95% confidence interval 0.74-0.90). The optimal cut-off point of the MHI-5 was 70. MHI-5 ?70 had 77 sensitivity, 72 specificity, 44 positive predicting value and 91% negative predicting value with the presence of depressive symptoms determined with BDI ?16.ConclusionsThe MHI-5 may help clinicians to screen for depressive symptoms in dialysis patients without using an additional depression screening questionnaire once the SF-36 is completed. A cut-off value of 70 can be used safely for the purposes of screening applications.
HubMed – depression
PC games can help in treating teen depression
Filed under: Depression Treatment
AUCKLAND: Long viewed as a contributing factor in teenage isolation, computer games are now being used to treat adolescent depression in an innovative New Zealand programme. Rather than simply encouraging players to engage in mindless destruction …
Read more on Times of India
Wife: Rep. Jesse Jackson Jr. getting treatment but 'still very depressed'
Filed under: Depression Treatment
(CNN) — The wife of Rep. Jesse Jackson Jr. detailed to a Chicago newspaper her husband's "collapse" and his last two months getting treated for gastrointestinal and mental health issues, saying he's still "very depressed" though showing some progress.
Read more on Los Angeles Wave Newspapers
Amoryn – Depression & AnxietyAMORYN works by increasing the levels of all four of the brain’s “feel good” neurotransmitters. By providing an all-natural boost …
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