Rehab Centers: Bisphosphonates Reduced the Risk of Acute Myocardial Infarction: A 2-Year Follow-Up Study.
Bisphosphonates reduced the risk of acute myocardial infarction: a 2-year follow-up study.
Filed under: Rehab Centers
Osteoporos Int. 2012 Nov 14;
Kang JH, Keller JJ, Lin HC
This population-based matched cohort analysis explored the effects of bisphosphonate treatment on acute myocardial infarction (AMI). We found that patients who received bisphosphonate therapy had a lower risk of AMI during a 2-year follow-up period (hazard ratio (HR)?=?0.35). Our data support that bisphosphonates may provide protective effects against cardiovascular events. INTRODUCTION: Although bisphosphonates have been suggested to have anti-atherosclerotic effects in animal models, evidence in human subjects is still conflicting. Therefore, this study aimed to explore the effects of bisphosphonate treatment on AMI using a population-based cohort study. METHODS: We identified 1,548 patients who received bisphosphonate therapy for osteoporotic fractures and randomly extracted 4,644 subjects with vertebral or hip fractures as a comparison cohort. Each patient was individually tracked for 2 years to identify those who subsequently suffered an AMI. Stratified Cox proportional hazards regressions were performed to assess the effect of bisphosphonate treatment on the risk of AMI. RESULTS: Six (0.4 %) of the patients who received bisphosphonate therapy and 49 (1.1 %) of the comparison subjects suffered an AMI during the 2-year follow-up period. The incidence rate of AMI was 1.94 (95 % CI?=?0.79-4.03) per 1,000 person-years in patients who received bisphosphonate therapy and 5.28 (95 % CI?=?3.95-6.92) per 1,000 person-years in comparison patients. Regression analysis revealed that patients who received bisphosphonate therapy had a lower hazard of AMI during the 2-year follow-up period than comparison patients (HR?=?0.37, 95 % CI?=?0.16-0.85, p?=?0.020). After censoring cases that died from non-AMI causes and adjusting for both demographic and risk factors, the HR of AMI for patients who received bisphosphonate therapy was 0.35 (95 % CI?=?0.14-0.84, p?=?0.020) than that of comparison patients. CONCLUSIONS: Patients who received bisphosphonate therapy had a lower risk of AMI during the 2-year follow-up period. Our data support that bisphosphonates may provide protective effects against cardiovascular events.
HubMed – rehab
Functional effect of transient transurethral catheterization on micturition in women: comment.
Filed under: Rehab Centers
Int Urogynecol J. 2012 Nov 15;
Valentini FA, Nelson PP
An overview of risk factors for poor neurodevelopmental outcome associated with prematurity.
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World J Pediatr. 2012 Nov; 8(4): 293-300
Xiong T, Gonzalez F, Mu DZ
BACKGROUND: Preterm birth is a major cause of neonatal mortality and morbidity. While advances in medical care have improved the survival of preterm infants, neurodevelopmental problems persist in this population. This article aims to review factors associated with their neurodevelopmental outcomes. DATA SOURCES: English language studies of neurodevelopmental outcomes in preterm infants were retrieved from PubMed. A total of 100 related publications were included. RESULTS: Early gestational age and birth weight are the most significant predictors of poor long-term neurological outcome. Structural changes of the brain, infection, male gender and neonatal intensive care unit course are also important factors affecting eventual outcome. Other complex biological and socio-economic factors, which extend from prenatal through postnatal periods, up through and including adulthood, also affect the trajectory of brain development in preterm infants. CONCLUSIONS: Neurodevelopmental problems continue to affect the preterm population. There is a critical need for collaboration among geneticists, obstetricians, pediatricians, and neuroimaging and rehabilitation experts to determine early predictive factors and neuroprotective therapies to properly treat or prevent poor neurodevelopmental outcomes in these infants.
HubMed – rehab
Christian Drug Rehab Center – Step 4 – Christian drug rehab center – Step 4 to successful recovery www.therecoveryplace.net (877) 231-1827 Charlotte, clinician in the Christian alcohol and drug rehab program at The Recovery Place, talks about step 4 from the Christian 12 steps to recovery. Step 4 involves writing down the things you resent, regret or fear and the relationships you have with those around you. This way you can recognize your fears or any dysfunctional patterns in your relationships. As other steps indicate, it is imperative to stay honest with yourself throughout the recovery process; first, by admitting your shortcomings and then by taking an ongoing inventory of them to refrain from falling back into destructive behavior. The Recovery Place Christian drug and alcohol rehab program utilizes the 12 Steps to recovery by implementing each step’s significance within addiction recovery.
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