Food and Drug Administration

Human Skin Keratinocytes Can Be Reprogrammed to Express Neuronal Genes and Proteins After a Single Treatment With Decitabine.

Human skin keratinocytes can be reprogrammed to express neuronal genes and proteins after a single treatment with decitabine.

Biores Open Access. 2013 Jun; 2(3): 217-21
Bickenbach JR, Tomanek-Chalkley A, Wiechert S, Winter MC

Patient-specific cell replacement therapy is fast… Continue reading

A Brief Summary of Psychiatric Nursing


 

A Brief Summary of Psychiatric Nursing – Nurses who focus on the patient with mental disorder, they are often called psychiatric nurse. They involve in the treatment of patient or bipolar patients. …

 

Vortioxetine, a new multimodal agent… Continue reading

Nanoparticle Albumin Bound Paclitaxel in the Treatment of Human Cancer: Nanodelivery Reaches Prime-Time?

Nanoparticle albumin bound Paclitaxel in the treatment of human cancer: nanodelivery reaches prime-time?

J Drug Deliv. 2013; 2013: 905091
Cucinotto I, Fiorillo L, Gualtieri S, Arbitrio M, Ciliberto D, Staropoli N, Grimaldi A, Luce A, Tassone P, Caraglia M,… Continue reading

US Approves “New Class” of Diabetes Drug, Under Review in Canada.

US approves “new class” of diabetes drug, under review in Canada.

CMAJ. 2013 Jun 3;
Lange-Chenier H

HubMed – drug

 

Medicare Covers The Majority Of FDA-Approved Devices And Part B Drugs, But Restrictions And Discrepancies Remain.

Health Aff… Continue reading

Beyond Anti-VEGF: Dual-Targeting Antiangiogenic and Antiproliferative Therapy.

Beyond anti-VEGF: dual-targeting antiangiogenic and antiproliferative therapy.

Am J Transl Res. 2013; 5(4): 393-403
Chen CT, Hung MC

Antiangiogenesis is a promising antitumor strategy that inhibits tumor vascular formation to suppress tumor growth. Specifically, targeting VEGF has shown therapeutic… Continue reading

Comment on “ApoE-Directed Therapeutics Rapidly Clear ?-Amyloid and Reverse Deficits in AD Mouse Models”

Comment on “ApoE-Directed Therapeutics Rapidly Clear ?-Amyloid and Reverse Deficits in AD Mouse Models”

Science. 2013 May 24; 340(6135): 924
Price AR, Xu G, Siemienski ZB, Smithson LA, Borchelt DR, Golde TE, Felsenstein KM

Cramer et al. (Reports, 23… Continue reading

Evaluation of a New Nonnvasive Device in Determining Hemoglobin Levels in Emergency Department Patients.

Evaluation of a New Nonnvasive Device in Determining Hemoglobin Levels in Emergency Department Patients.

West J Emerg Med. 2013 May; 14(3): 283-286
Knutson T, Della-Giustina D, Tomich E, Wills B, Luerssen E, Reynolds P

Introduction: The Masimo Radical-7 Pulse CO-Oximeter is a medical device recently approved by the US Food and Drug Administration that performs noninvasive oximetry and estimated venous or arterial hemoglobin measurements. A portable, noninvasive device that rapidly measures hemoglobin concentration could be useful in both austere and modern hospital settings. The objective of this study is to determine the degree of variation between the device’s estimated hemoglobin measurement and the actual venous hemoglobin concentration in undifferentiated emergency department (ED) patients. Methods: We conducted a prospective, observational, cross-sectional study of adult patients presenting to the ED. The subjects consisted of a convenience sample of adult ED patients who required a complete blood count as part of their care in the ED. A simultaneous probe hemoglobin was obtained and recorded. Results: Bias between probe and laboratory hemoglobin measurements was -0.5 (95% confidence interval, – 0.8 to -0.1) but this was not statistically significant from 0 (t 0.05,124 = 0.20, P > 0.5). The limits of agreement… Continue reading

Delirium Associated With Donepezil in a Patient With Alzheimer’s Disease: A Case Report.

Delirium associated with donepezil in a patient with Alzheimer’s disease: a case report.

Iran J Psychiatry. 2013 Mar; 8(1): 59-60
Mollazadeh-Moghaddam K, Jamali A, Adili-Aghdam F, Akhondzadeh S

Donepezil, a member of the acetylcholinesterase inhibitor family, is approved for… Continue reading

Characterization of Prescription Opioid Abuse in the United States: Focus on Route of Administration.

Characterization of prescription opioid abuse in the United States: focus on route of administration.

J Pain Palliat Care Pharmacother. 2012 Dec; 26(4): 348-61
Kirsh K, Peppin J, Coleman J

Prescription opioids are prescribed increasingly for the management of chronic… Continue reading

[Antibiotic-Associated Diarrhea in Clinical Practice].

[Antibiotic-associated diarrhea in clinical practice].

Ter Arkh. 2013; 85(2): 85-8

Antibiotic-associated diarrhea (AAD) is considered to mean at least 3 shapeless stool episodes within 2 or more consecutive days when using antibacterial agents. Due to the fact that antibiotics… Continue reading