Multidrug resistance

Functionalized Graphene Oxide Mediated Adriamycin Delivery and miR-21 Gene Silencing to Overcome Tumor Multidrug Resistance in Vitro.

Functionalized Graphene Oxide Mediated Adriamycin Delivery and miR-21 Gene Silencing to Overcome Tumor Multidrug Resistance In Vitro.

PLoS One. 2013; 8(3): e60034
Zhi F, Dong H, Jia X, Guo W, Lu H, Yang Y, Ju H, Zhang X, Hu… Continue reading

FDA Approves First Drug Formulated for Children With Rare Brain Tumor.

FDA approves first drug formulated for children with rare brain tumor.

Home Healthc Nurse. 2013 Feb; 31(2): 56-7

HubMed – drug

 

Hypoxia Antagonizes Glucose Deprivation on Interleukin 6 Expression in an Akt Dependent, but HIF-1/2? Independent Manner.

PLoS… Continue reading

Deoxyhypusine Hydroxylase From Plasmodium Vivax, the Neglected Human Malaria Parasite: Molecular Cloning, Expression and Specific Inhibition by the 5-LOX Inhibitor Zileuton.

Deoxyhypusine Hydroxylase from Plasmodium vivax, the Neglected Human Malaria Parasite: Molecular Cloning, Expression and Specific Inhibition by the 5-LOX Inhibitor Zileuton.

PLoS One. 2013; 8(3): e58318
Atemnkeng VA, Pink M, Schmitz-Spanke S, Wu XJ, Dong LL, Zhao KH, May… Continue reading

Treating Tuberculosis: Time to Introduce Fixed-Dose Drug Combinations.

Treating Tuberculosis: Time to Introduce Fixed-Dose Drug Combinations.

J Young Pharm. 2012 10; 4(4): 199-200
Manikandan S

HubMed – drug

 

The Role of Phenethyl Isothiocyanate on Bladder Cancer ADM Resistance Reversal and Its Molecular Mechanism.

Anat Rec (Hoboken)… Continue reading

[Research Progress of Self-Assembled Beads Drug Delivery System Prepared From Cyclodextrins and Oils].

[Research progress of self-assembled beads drug delivery system prepared from cyclodextrins and oils].

Yao Xue Xue Bao. 2012 Dec; 47(12): 1582-6
Liu C, Yi T

Recently, increasing attention has been paid to beads, an innovative self-assembled drug delivery system… Continue reading

Gene Expression and Thiopurine Metabolite Profiling in Inflammatory Bowel Disease – Novel Clues to Drug Targets and Disease Mechanisms?

Gene expression and thiopurine metabolite profiling in inflammatory bowel disease – novel clues to drug targets and disease mechanisms?

PLoS One. 2013; 8(2): e56989
Haglund S, Almer S, Peterson C, Söderman J

Thiopurines are effective to induce and maintain remission in inflammatory bowel disease (IBD). The methyl thioinosine monophosphate (meTIMP)/6-thioguanine nucleotide (6-TGN) concentration ratio has been associated with drug efficacy. Here we explored the molecular basis of differences in metabolite profiles and in relation to disease activity.Transcriptional profiles in blood samples from an exploratory IBD-patient cohort (n?=?21) with a normal thiopurine S-methyltransferase phenotype and meTIMP/6-TGN ratios >20, 10.0-14.0 and ?4, respectively, were assessed… Continue reading

Gynostemma Pentaphyllum Tea Improves Insulin Sensitivity in Type 2 Diabetic Patients.

Gynostemma pentaphyllum Tea Improves Insulin Sensitivity in Type 2 Diabetic Patients.

J Nutr Metab. 2013; 2013: 765383
Huyen VT, Phan DV, Thang P, Hoa NK, Ostenson CG

Aims. To evaluate the effect of the traditional Vietnamese herb Gynostemma pentaphyllum… Continue reading

Proteomic Profiling of Trastuzumab (Herceptin(R))-Sensitive and -Resistant SKBR-3 Breast Cancer Cells.

Proteomic Profiling of Trastuzumab (Herceptin(R))-sensitive and -resistant SKBR-3 Breast Cancer Cells.

Filed under: Drug and Alcohol Rehabilitation

Anticancer Res. 2013 Feb; 33(2): 489-503
DI Cara G, Marengo G, Albanese NN, Marabeti MR, Musso R, Cancemi P, Pucci-Minafra I

The… Continue reading

Drug and Alcohol Rehabilitation: Prospective Surveillance for Cardiac Adverse Events in Healthy Adults Receiving Modified Vaccinia Ankara Vaccines: A Systematic Review.

Prospective surveillance for cardiac adverse events in healthy adults receiving modified vaccinia ankara vaccines: a systematic review.

Filed under: Drug and Alcohol Rehabilitation

PLoS One. 2013; 8(1): e54407
Elizaga ML, Vasan S, Marovich MA, Sato AH, Lawrence DN, Chaitman… Continue reading

Chlorotoxin Fused to IgG-Fc Inhibits Glioblastoma Cell Motility via Receptor-Mediated Endocytosis.

Chlorotoxin Fused to IgG-Fc Inhibits Glioblastoma Cell Motility via Receptor-Mediated Endocytosis.

Filed under: Drug and Alcohol Rehabilitation

J Drug Deliv. 2012; 2012: 975763
Kasai T, Nakamura K, Vaidyanath A, Chen L, Sekhar S, El-Ghlban S, Okada M, Mizutani A,… Continue reading