The Challenges of Eating a Healthy and Sustainable Diet.

The challenges of eating a healthy and sustainable diet.

Filed under: Eating Disorders

Am J Clin Nutr. 2012 Aug 8;
Clonan A, Holdsworth M

HubMed – eating

 

Bone metabolism in anorexia nervosa: molecular pathways and current treatment modalities.

Filed under: Eating Disorders

Osteoporos Int. 2012 Aug 9;
Howgate DJ, Graham SM, Leonidou A, Korres N, Tsiridis E, Tsapakis E

Eating disorders are associated with a multitude of metabolic abnormalities which are known to adversely affect bone metabolism and structure. We aimed to comprehensively review the literature on the effects of eating disorders, particularly anorexia nervosa (AN), on bone metabolism, bone mineral density (BMD), and fracture incidence. Furthermore, we aimed to highlight the risk factors and potential management strategies for patients with eating disorders and low BMD. We searched the MEDLINE/OVID (1950-July 2011) and EMBASE (1980-July 2011) databases, focussing on in vitro and in vivo studies of the effects of eating disorders on bone metabolism, bone mineral density, and fracture incidence. Low levels of estrogen, testosterone, dehydroepiandrosterone, insulin-like growth factor-1 (IGF-1), and leptin, and high levels of cortisol, ghrelin, and peptide YY (PYY) are thought to contribute to the ‘uncoupling’ of bone turnover in patients with active AN, leading to increased bone resorption in comparison to bone formation. Over time, this results in a high prevalence and profound degree of site-specific BMD loss in women with AN, thereby increasing fracture risk. Weight recovery and increasing BMI positively correlate with levels of IGF-1 and leptin, normalisation in the levels of cortisol, as well as markers of bone formation and resorption in both adolescent and adult patients with AN. The only treatments which have shown promise in reversing the BMD loss associated with AN include: physiologic dose transdermal and oral estrogen, recombinant human IGF-1 alone or in combination with the oral contraceptive pill, and bisphosphonate therapy.
HubMed – eating

 

Frontotemporal dementia due to C9ORF72 mutations: Clinical and imaging features.

Filed under: Eating Disorders

Neurology. 2012 Aug 8;
Sha SJ, Takada LT, Rankin KP, Yokoyama JS, Rutherford NJ, Fong JC, Khan B, Karydas A, Baker MC, Dejesus-Hernandez M, Pribadi M, Coppola G, Geschwind DH, Rademakers R, Lee SE, Seeley W, Miller BL, Boxer AL

OBJECTIVE:To describe the phenotype of patients with C9FTD/ALS (C9ORF72) hexanucleotide repeat expansion. METHODS:A total of 648 patients with frontotemporal dementia (FTD)-related clinical diagnoses and Alzheimer disease (AD) dementia were tested for C9ORF72 expansion and 31 carried expanded repeats (C9+). Clinical and neuroimaging data were compared between C9+ (15 behavioral variant FTD [bvFTD], 11 FTD-motor neuron disease [MND], 5 amyotrophic lateral sclerosis [ALS]) and sporadic noncarriers (48 bvFTD, 19 FTD-MND, 6 ALS). RESULTS:All C9+ patients displayed clinical syndromes of bvFTD, ALS, or FTD-MND. At first evaluation, C9+ bvFTD patients had more delusions and greater impairment of working memory, but milder eating dysregulation compared to bvFTD noncarriers. C9+FTD-MND patients had a trend for longer survival and had an earlier age at onset than FTD-MND noncarriers. Voxel-based morphometry demonstrated more thalamic atrophy in FTD and FTD-MND carriers than in noncarriers. CONCLUSIONS:Patients with the C9ORF72 hexanucleotide repeat expansion develop bvFTD, ALS, or FTD-MND with similar clinical and imaging features to sporadic cases. Other FTD spectrum diagnoses and AD dementia appear rare or absent among C9+ individuals. Longer survival in C9+ FTD-MND suggests slower disease progression and thalamic atrophy represents a novel and unexpected feature.
HubMed – eating

 

Pine terpenoid defences in the mountain pine beetle epidemic and in other conifer pest interactions: specialized enemies are eating holes into a diverse, dynamic and durable defence system.

Filed under: Eating Disorders

Tree Physiol. 2012 Aug; 32(8): 943-5
Bohlmann J

HubMed – eating

 

 

Recovering from Eating Disorders – Eating disorders affect up to 24 million Americans, most of them girls and young women. For National Eating Disorder Awareness Week, Dr. Jennifer Ashton talks with Project HEAL’s Liana Rosenman about her organization’s mission and her personal story.

 

Hunger games: Some female athletes battle eating disorders

Filed under: Eating Disorders

HOUSTON—Swimmer Amanda Beard, gymnast Nadia Comaneci, and skater Nancy Kerrigan at their peaks were some of the fittest and fastest in the world, but behind their public victories were private battles with eating disorders. Much emphasis is placed …
Read more on KHOU

 

Recognition of Binge Eating Disorder Long Overdue, Says Dr. Gregory Jantz of …

Filed under: Eating Disorders

Binge eating disorder will be listed with eating disorders more familiar to the general public, such as anorexia and bulimia, in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders, or DSM-5. The American Psychiatric …
Read more on MarketWatch (press release)

 

Girls with eating disorders regain healthy fatty acid levels when their weight …

Filed under: Eating Disorders

"Essential fatty acid status is altered in eating disorders that result in weight loss" explains co-author Dr Ingemar Swenne from Uppsala University Children's Hospital. "This is important because deficiencies in polyunsaturated omega-3 essential fatty …
Read more on Medical Xpress

 

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